EnWave's proprietary Radiant Energy Vacuum ("REV") technology combines microwave energy with vacuum pressure to produce high-speed dehydration of live or active pharmaceuticals in sterile vials. This process is particularly suitable for creating room temperature stable pharmaceuticals containing live organisms such as viruses, bacteria and antibodies where an emphasis must be placed on maintaining the maximum possible survival rates of these organisms until they are delivered to a patient.

Production of dried vaccines storable at room temperatures for long periods of time would be considered a major industry breakthrough. Dried vaccines with long shelf-life could be shipped worldwide, stored without the need for expensive, constant refrigeration, and stockpiled to protect against pandemic diseases and bioterrorism. The current standard for dehydrating many liquid pharmaceuticals is freeze drying (“lyophilization”). This process is expensive, time consuming and often results in significant loss of live organism activity during dehydration.

EnWave has developed two versions of REV for use in drying live or active pharmaceuticals:

bioREV™ - a dehydration method for materials which require a gentler drying process without extreme temperature changes or freezing.

freezeREV™ - a dehydration method for frozen material where low moisture levels in the final product are imperative for long product shelf-life.

Both methods dry material in minutes compared to days required for conventional freeze drying, and both technologies are designed to offer the potential for significant reductions in processing costs through labour, raw material, energy and time savings.

bioREV™ and freezeREV™ technology is currently available as a single-vial prototype to collaboration partners.